Papers

61. Enantioconvergent synthesis of chiral fluorenols from racemic secondary alcohols via Pd(II)/chiral norbornene cooperative catalysis

Bo Ding†, Qilin Xue, Han Wei, Jiangwei Chen, Ze-Shui Liu, Hong Gang Cheng, Hengjiang Cong, Jianting Tang and Qianghui Zhou*

Chem. Sci. 2024, 15, 7975-7981.

DOI: 10.1039/d4sc01004c

60. Transition-Metal Catalyzed C−H Alkylation Using Epoxides as Alkylating Reagents

Ze-Shui Liu*, Danni Wang, Hong-Gang Cheng*, Qianghui Zhou

ChemCatChem. 2024, e202301764.

DOI: 10.1002/cctc.202301764

59. Synthesis of Planar Chiral Ferrocenes via Enantioselective Remote C–H Activation

Lan Zhou†, Hong-Gang Cheng†*, Lisha Li, Kevin Wu, Jing Hou, Chengkang Jiao, Shuang Deng, Zirui Liu, Jin-Quan Yu* and Qianghui Zhou*

Nat. Chem. 2023, 15, 815-823.

DOI: 10.1038/s41557-023-01176-3

（Highlighted by Science Bulletin ＆ Synfacts ＆ 科学网＆小柯化学＆武汉大学＆纳米人＆化学与材料科学＆ X-MOL）

58. Chemoenzymatic Synthesis of C14-functionalized Steroids

Fuzhen Song†, Mengmeng Zheng†, Junlin Wang, Huanhuan Liu, Zhi Lin, Benben Liu, Zixin Deng, Hengjiang Cong, Qianghui Zhou* and Xudong Qu*

Nat. Synth. 2023, 2, 729–739.

DOI: 10.1038/s44160-023-00280-z.

（Highlighted by 武汉大学）

57. Construction of Axially Chiral Biaryls via Atroposelective ortho-C–H Arylation of Aryl Iodides

Ze-Shui Liu†, Shuang Deng†, Qianwen Gao, Yu Hua, Hong-Gang Cheng, Xiaotian Qi* and Qianghui Zhou*

ACS Catal. 2023, 13, 2968–2980.

DOI: 10.1021/acscatal.2c06310.

56. Quick Assembly of 1-Alkylidenyl-tetrahydroisoquinolines via a Catellani Reaction/NBS-Mediated Cyclization Sequence and Synthetic Applications

Shihu Jia†, Miao Bai†, Siwei Zhou, Ruiqing Sheng, Hong-Gang Cheng* and Qianghui Zhou*

Sci. China Chem. 2023, 66, 3136-3140.

DOI: 10.1007/s11426-022-1526-7.

55. Additive-Enhanced Crystallization of Inorganic Perovskite Single Crystals for High-Sensitivity X-Ray Detection

Zexu Xue, Yingrui Wei, Hao Li, Jiali Peng, Fang Yao, Yong Liu, Sheng Wang, Qianghui Zhou, Qianqian Lin* and Zhiping Wang*

Small 2023, 19, 2207588.

DOI: 10.1002/smll.202207588.

54. Benzo-Fused Ring Toolbox Based on Palladium/Norbornene Cooperative Catalysis: Methodology Development and Applications in Natural Product Synthesis

Hong-Gang Cheng†, Shihu Jia† and Qianghui Zhou*

Acc. Chem. Res. 2023, 56, 573–591.

DOI: 10.1021/acs.accounts.2c00781.

（Highlighted by X-MOL）

53. Enantioselective Assembly of Ferrocenes with Axial and Planar Chiralities via Palladium/Chiral Norbornene Cooperative Catalysis

Jinxiang Ye^†, Lisha Li^†, Yiming You, Chengkang Jiao, Ziyang Cui, Yabin Zhang, Shihu Jia, Hengjiang Cong, Shanshan Liu, Hong-Gang Cheng* and Qianghui Zhou*

JACS Au 2023, 3, 384–390.

DOI: 10.1021/jacsau.2c00630.

（Highlighted by ACS美国化学会）

52. Modular One-Step Three-Component Assembly of Isochromans via Palladium/Norbornene Cooperative Catalysis

Xinping Zhang†, Han Wei†, Qiang Wei, Chenggui Wu, Chang Liu, Hong-Gang Cheng* and Qianghui Zhou*

Asian J. Org. Chem. 2023, 12, e202200642.

DOI:10.1002/ajoc.202200642.

51. A Concise Total Synthesis of (±)-Stepharine and (±)-Pronuciferine

Ruiming Chen†, Shihu Jia†, Yuning Man, Hong-Gang Cheng* and Qianghui Zhou*

Synthesis 2022, 54, ASAP.

DOI:10.1055/a-1984-0755.

50. Palladium-Catalyzed [4+3] Annulation of 2-Bromobiphenyls and Epoxides for the Assembly of Dihydrodibenzo[b,d] oxepines

Zipei Shen†, Lan Zhou†, Chenggui Wu, Qianghui Zhou* and Hong-Gang Cheng*

Org. Biomol. Chem. 2022, 20, 8869–8872.

DOI: 10.1039/D2OB01720B.

Graphical abstract: Palladium-catalyzed [4 + 3] annulation of 2-bromobiphenyls and epoxides for the assembly of dihydrodibenzo[b,d]oxepines

49. Pd-Catalyzed Asymmetric Allylic Alkylation of Indoles by a New Class of Axially Chiral Phosphine-Alkene Ligands

Shihu Jia, Siyuan Chen, Ze-Shui Liu, Hong-Gang Cheng^*, Qianghui Zhou^*

Chin. J. Org. Chem. 2022, 42, 3373–3381.

DOI: 10.6023/cjoc202209002.

48. From N–H Nitration to Controllable Aromatic Mononitration and Dinitration─The Discovery of a Versatile and Powerful N-Nitropyrazole Nitrating Reagent

Tao Yang, Xiaoqian Li, Shuang Deng, Xiaotian Qi, Hengjiang Cong, Hong-Gang Cheng, Liangwei Shi*, Qianghui Zhou* and Lin Zhuang*

JACS Au 2022, 2, 2152–2161.

DOI: 10.1021/jacsau.2c00413.

47. A Modular Approach for Diversity-Oriented Synthesis of 1,3-trans-Disubstituted Tetrahydroisoquinolines: Seven-Step Asymmetric Synthesis of Michellamines B and C

Miao Bai, Shihu Jia, Jingyang Zhang, Hong-Gang Cheng, Hengjiang Cong, Shanshan Liu, Zhiqian Huang, Yaoguo Huang, Xiaoming Chen and Qianghui Zhou*

Angew. Chem. Int. Ed. 2022, 61, e202205245.

DOI: 10.1002/anie.202205245.

（Highlighted by 武汉大学）

46. Eight-Step Asymmetric Synthesis of (–)-Berkelic Acid

Zhenjie Yang, Hong-Gang Cheng*, Ruiming Chen, Liming Cao, Qiang Wei, Qingqing Wang and Qianghui Zhou*

Synthesis 2022, 54, 4691–4702.

DOI: 10.1055/a-1799-0459.

45. Pd/NBE/Chiral Amino Acid Cooperative Catalysis for Enantioselective Construction of All-Carbon Brideged Ring Systems

Jinxiang Ye and Qianghui Zhou*

Chin. J. Org. Chem. 2022, 42, 307–309. (Invited highlight.)

DOI: 10.6023/cjoc202200003

44. Recent Advances in Catalytic Nonenzymatic Kinetic Resolution of Tertiary Alcohols

Bo Ding†, Qilin Xue†, Shihu Jia, Hong-Gang Cheng* and Qianghui Zhou*

Synthesis 2022, 54, 1721–1732.

DOI: 10.1055/a-1712-0912.

43. Diversity-Oriented Synthesis of Flavones and Isoflavones via Palladium/Norbornene Cooperative Catalysis

Yuanyuan Ma, Qianwen Gao, Lan Zhou, Shanshan Liu, Hong–Gang Cheng, and Qianghui Zhou*

Chin. J. Chem. 2022, 40, 675–680.

DOI:10.1002/cjoc.202100693.

42. Catalytic Synthesis of Atropisomeric o-Terphenyls with 1,2-Diaxes via Axial-to-Axial Diastereoinduction

Qianwen Gao, Chenggui Wu, Shuang Deng, Lisha Li, Ze-Shui Liu, Yu Hua, Jinxiang Ye, Chang Liu, Hong-Gang Cheng, Hengjiang Cong, Yinchun Jiao, and Qianghui Zhou*

J. Am. Chem. Soc. 2021, 143, 7253–7260.

DOI: 10.1021/jacs.1c02405.

41. Diversity-Oriented Functionalization of 2-Pyridones and Uracils

Yong Shang†, Chenggui Wu†, Qianwen Gao, Chang Liu, Lisha Li, Xinping Zhang, Hong-Gang Cheng, Shanshan Liu and Qianghui Zhou*

Nat. Commun. 2021, 12, 2988.

DOI: 10.1038/s41467-021-23058-3.

40. An Axial-to-Axial Chirality Transfer Strategy for Atroposelective Construction of C–N Axial Chirality

Ze-Shui Liu†, Pei-Pei Xie†, Yu Hua, Chenggui Wu, Yuanyuan Ma, Jiangwei, Chen, Hong-Gang Cheng, Xin Hong* and Qianghui Zhou*

Chem 2021, 7, 1917–1932.

DOI:10.1016/j.chempr.2021.04.005.

（Highlighted by X-MOL）

39. C−H Hetero-Functionalization of Arenes through Palladacyclopentane-Type Intermediates

Liming Cao†, Yu Hua†, Hong-Gang Cheng* and Qianghui Zhou*

Org. Chem. Front. 2021, 8, 3883–3914.

DOI: 10.1039/D0QO01350A.

38. Kinetic Resolution of Tertiary Benzyl Alcohols via Palladium/Chiral Norbornene Cooperative Catalysis

Yu Hua†, Ze-Shui Liu†, Pei-Pei Xie, Bo Ding, Hong-Gang Cheng, Xin Hong* and Qianghui Zhou*

Angew. Chem. Int. Ed. 2021, 60, 12824–12828. (VIP)

DOI: 10.1002/anie.202103428

（Highlighted by X-MOL）

37. Pd/Chiral Phosphoric Acid-Catalyzed Enantioselectiveβ-C(sp3)—H Arylation of Thiamides

Lan Zhou, Honggang Cheng* and Qianghui Zhou*

Chin. J. Org. Chem. 2020, 40, 3009–3011.(Invited highlight.)

DOI: 10.6023/cjoc202000061.

36. One-Step Synthesis of THIQ via a Catellani Strategy

Miao Bai, Liming Cao, Honggang Cheng and Qianghui Zhou*

Trends in Chemistry 2021, 3, 248–249.

DOI: 10.1016/j.trechm.2020.11.003.

35. A Concise Total Synthesis of (–)-Berkelic Acid

Hong-Gang Cheng†, Zhenjie Yang†, Ruiming Chen, Liming Cao, Wen-Yan Tong, Qiang Wei, Qingqing Wang, Chenggui Wu, Shuanglin Qu* and Qianghui Zhou*

Angew. Chem. Int. Ed. 2021, 60, 5141–5146.

DOI: 10.1002/anie.202014660.

（Highlighted by 武汉大学）

34. Molecular Vises for Precisely Positioning Ligands near Catalytic Metal Centers in Metal-Organic Framework

Wei Yan, Shenhui Li*, Tao Yang, Yucong Xia, Xinrui Zhang, Chao Wang, Zier Yan, Feng Deng*, Qianghui Zhou and Hexiang Deng*

J. Am. Chem. Soc. 2020, 142, 16182–16187.

DOI: 10.1021/jacs.0c07450.

33. Turning Constraint into Opportunity: Development of a Four-Component Catellani Reaction

Hong-Gang Cheng* and Qianghui Zhou*

Sci. Bull. 2020, 65, 1961–1963.

DOI: 10.1016/j.scib.2020.08.024.

32. Rapid Access to Tetracyclic Core of Wortmannin via An Intramolecular Reductive Olefin Coupling Strategy

Ying Hu, Miao Bai, Ying Yang, Jiangyan Tian and Qianghui Zhou*

Org. Lett. 2020, 22, 6308–6312.

DOI: 10.1021/acs.orglett.0c02135.

31. Construction of Axial Chirality via Palladium/Chiral Norbornene Cooperative Catalysis

Ze-Shui Liu, Yu Hua†, Qianwen Gao†, Yuanyuan Ma, Hua Tang, Yong Shang, Hong-Gang Cheng and Qianghui Zhou*

Nat. Catal. 2020, 3, 727–733.

DOI: 10.1038/s41929-020-0494-1.

30. Precise Functionalization of Remote C―H Bonds

Ze-Shui Liu, Hong-Gang Cheng and Qianghui Zhou*

Chem. Res. Chinese Universities 2020, 36, 727–728.

DOI: 10.1007/s40242-020-0158-3.

29. Alkyl Tosylates as Alkylating Reagents for the Catellani Reaction

Qianwen Gao, Ze-Shui Liu, Yu Hua, Siwei Zhou, Hong-Gang Cheng* and Qianghui Zhou*

Synthesis 2020, 52, 834–846.

DOI: 10.1055/s-0039-1690801.

28. Epoxide as a Dual-functionalized Alkylating Reagent in Catellani Reactions for the Assembly of Heterocycles

Chenggui Wu, Hong-Gang Cheng* and Qianghui Zhou*

Synlett 2020, 31, 829–837.

DOI: 10.1055/s-0039-1690779.

27. Phytosphinganine Affects Plasmodesmata Permeability via Facilitating PDLP5-Stimulated Callose Accumulation in Arabidopsis

Ning-Jing Liu, Tao Zhang, Zhao-Hui Liu, Xin Chen, Hui-Shan Guo, Bai-Hang Ju, Yuan-Yuan Zhang, Guo-Zhu Li, Qianghui Zhou, Yong-Mei Qin* and Yu-Xian Zhu

Mol. Plant 2020, 13, 128–143.

DOI: 10.1016/j.molp.2019.10.013.

26. Synthesis of Benzofused Dioxabicycle Scaffolds via a Catellani Strategy

Chenggui Wu, Xinjun Yang, Yong Shang, Hong-Gang Cheng, Wei Yan and Qianghui Zhou*

Org. Lett. 2019, 21, 8938–8942.

DOI: 10.1021/acs.orglett.9b03228.

25. Modular Dual-Tasked C-H Methylation via the Catellani Strategy

Qianwen Gao, Yong Shang, Fuzhen Song, Jinxiang Ye, Ze-Shui Liu, Lisha Li, Hong-Gang Cheng and Qianghui Zhou*

J. Am. Chem. Soc. 2019, 141, 15986–15993. (selected as cover)

DOI: 10.1021/jacs.9b07857.

（Highlighted by 武汉大学）

24. Three-Step Total Synthesis of Ramelteon via a Catellani Strategy

Shijun Gao, Guangyin Qian, Hao Tang, Zuo Yang and Qianghui Zhou^*

ChemCatChem. 2019, 11, 5762–5765.

DOI: 10.1002/cctc.201901355.

23. Amination of Pinacol Arylborates via Palladium(II)/Norbornene Catalysis for Anilines Synthesis

Shuqing Chen†, Peng Wang†,Hong-Gang Cheng, Chihui Yang and Qianghui Zhou^*

Chem. Sci. 2019, 10, 8384–8389.

DOI: 10.1039/C9SC02759A.

22. A Biocatalytic Hydroxylation Enabled Unified Approach to C19-H hydroxylated Steroids

Junlin Wang†, Yanan Zhang†, Huanhuan Liu, Yong Shang, Linjun Zhou, Penglin Wei, Wen-Bing Yin, Zixin Deng, Xudong Qu* and Qianghui Zhou*

Nat. Commun. 2019, 10, 3378.

DOI: 10.1038/s41467-019-11344-0.

21. A Palladium/Norbornene Cooperative Catalysis to Access N-Containing Bridged Scaffolds

Qianwen Gao, Ze-Shui Liu, Yu Hua, Lisha Li, Hong-Gang Cheng, Hengjiang Cong and Qianghui Zhou*

Chem. Comm. 2019, 55, 8816–8819.

DOI: 10.1039/C9CC03126J.

20. Chemoselective Borono-Catellani Arylation for Unsymmetrical Biaryls Synthesis

Peng Wang†, Shuqing Chen†, Zhiyu Zhou, Hong-Gang Cheng, and Qianghui Zhou*

Org. Lett. 2019, 21, 3323–3327.

DOI: 10.1021/acs.orglett.9b01072.

19. 5-Norbornene-2-carboxylic acid: Another catalytic mediator for Catellani-Type reactions

Ze-Shui Liu, Guangyin Qian, Qianwen Gao, Peng Wang, Hong-Gang Cheng, Yu Hua and Qianghui Zhou*

Tetrahedron 2019, 75, 1774–1780.

DOI: 10.1016/j.tet.2019.01.033.

18. The Pd(II)‐Initiated Catellani‐Type Reactions

Hong-Gang Cheng, Shuqing Chen, Ruiming Chen, and Qianghui Zhou*

Angew. Chem. Int. Ed. 2019, 58, 5832–5844.

DOI: 10.1002/anie.201813491.

17. Bridgehead-Modified NBEs: A Solution to ortho-Constraint in Catellani-Type Reactions

Hong-Gang Cheng and Qianghui Zhou*

Chem 2018, 4, 1775–1777. (Preview)

DOI: 10.1016/j.chempr.2018.07.013.

16. The Alkylating Reagents Employed in Catellani‐Type Reactions

Ze-Shui Liu, Qianwen Gao, Hong-Gang Cheng* and Qianghui Zhou*

Chem. Eur. J. 2018, 24, 15461–15476.

DOI: 10.1002/chem.201802818.

15. Modular One‐Step Three‐Component Synthesis of Tetrahydroisoquinolines via a Catellani Strategy

Guangyin Qian, Miao Bai, Shijun Gao, Han Chen, Siwei Zhou, Hong-Gang Cheng*, Wei Yan and Qianghui Zhou*

Angew. Chem. Int. Ed. 2018, 57, 10980–10984.

DOI: 10.1002/anie.201806780.

14. Convergent Syntheses of 2,3-Dihydrobenzofurans via a Catellani Strategy

Chenggui Wu, Hong-Gang Cheng*, Ruiming Chen†, Han Chen†, Ze-Shui Liu, Jingyang Zhang, Yuming Zhang, Yuxin Zhu, Zhi Geng and Qianghui Zhou*

Org. Chem. Front. 2018, 5, 2533–2536. (selected as Front cover)

DOI: 10.1039/C8QO00348C.

13. The Discovery of a Palladium(II)-Initiated Borono-Catellani Reaction

Shuqing Chen^†, Ze-Shui Liu^†, Tao Yang, Yu Hua, Zhiyu Zhou, Hong-Gang Cheng and Qianghui Zhou*

Angew. Chem. Int. Ed. 2018, 57, 7161–7165.

DOI: 10.1002/anie.201803865.

（Highlighted by 武汉大学）

12. A Palladium/Norbornene Cooperative Catalysis to Access Tetrahdronaphthalenes and Indanes with a Quaternary Center

Zeshui Liu†, Guangyin Qian†, Qianwen Gao, Peng Wang, Hong-Gang Cheng, Qiang Wei, Qi Liu, and Qianghui Zhou*

ACS Catalysis 2018, 8, 4783–4788.

DOI: 10.1021/acscatal.8b00975.

（Highlighted by 武汉大学）

11. USP2a Supports Metastasis by Tuning TGF- β Signaling

Yin Zhao, Xiaomeng Wang, Qingqing Wang, Qianghui Zhou and Bo Zhong* et al

Cell Reports 2018, 22, 2442–2454.

DOI: 10.1016/j.celrep.2018.02.007.

10. Epoxides as Alkylating Reagents for the Catellani Reaction

Hong-Gang Cheng, Chenggui Wu, Han Chen†, Ruiming Chen†, Guangyin Qian, Zhi Geng, Qiang Wei, Yuanyuan Xia, Jingyang Zhang, Yuming Zhang and Qianghui Zhou*

Angew. Chem. Int. Ed. 2018, 57, 3444–3448. (selected as cover)

DOI: 10.1002/anie.201800573.

9. The Liebeskind–Srogl Cross-Coupling Reaction and its Synthetic Applications

Hong-Gang Cheng, Han Chen, Yue Liu and Qianghui Zhou*

Asian J. Org. Chem. 2018, 7, 490–508.

DOI: 10.1002/ajoc.201700651.

8. Metal-Catalyzed Enyne Cycloisomerization in Natural Product Total Synthesis

Ying Hu, Miao Bai, Ying Yang and Qianghui Zhou*

Org. Chem. Front. 2017, 4, 2256–2275.

DOI: 10.1039/C7QO00702G.

Prior to WHU

7. Development of a Concise Synthesis of Ouabagenin and Hydroxylated Corticosteroid Analogues. H. Renata#, Qianghui Zhou#, G. Dünstl, J. Felding, R. Merchant, C.-H. Yeh, P. S. Baran*, J. Am. Chem. Soc., 2015, 137, 1330. [Supporting Information]

6. C–H Methylation of Heteroarenes Inspired by Radical SAM Methyl Transferase. J. Gui#, Qianghui Zhou#, C.-M. Pan, Y. Yabe, A. C. Burns, M. R. Collins, M. A. Ornelas, Y. Ishihara, P. S. Baran*, J. Am. Chem. Soc., 2014, 136, 4853. [Supporting Information]

5. Bioconjugation by Native Chemical Tagging of C–H Bonds. Qianghui Zhou, J. Gui, C.-M. Pan, E. Albone, X.Cheng, E. M. Suh, L. Grasso, Y. Ishihara, P. S. Baran*, J. Am. Chem. Soc., 2013, 135, 12994. [Supporting Information]

4. Direct Synthesis of Fluorinated Heteroarylether Bioisosteres. Qianghui Zhou, A. Ruffoni, R. Gianatassio1, Y. Fujiwara, E. Sella, D. Shabat, P. S. Baran*, Angew. Chem. Int. Ed., 2013, 52, 3949. [Supporting Information]

3. Strategic Redox Relay Enables A Scalable Synthesis of Ouabagenin, A Bioactive Cardenolide. Hans Renata, Qianghui Zhou, Phil S. Baran* Science, 2013, 339, 59. [Supporting Information]

2. Scalable, Divergent Synthesis of Meroterpenoids via “Borono-sclareolide. Darryl D. Dixon, Jonathan W. Lockner, Qianghui Zhou, and Phil S. Baran* J. Am. Chem. Soc.,2012, 134 (20), 8432–8435. [Supporting Information]

1. Asymmetric, Protecting-Group-Free Total Synthesis of (-)-Englerin A . Qianghui Zhou, X. Chen, D. Ma* Angew. Chem. Int. Ed., 2010, 49, 3513. [Supporting Information]